Tanshinone IIA, a melanogenic ingredient basis of Salvia miltiorrhiza Bunge
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چکیده
منابع مشابه
Determination of tanshinone IIA in Salvia miltiorrhiza Bunge extract and its effect on ischemia-reperfusion injury
To establish an HPLC method for determination of tanshinone IIA in Salvia miltiorrhiza Bunge extract, and observe the protective effect of Salvia miltiorrhiza extract on myocardial ischemia-reperfusion injury in rats. Column used is a Diamonsil C18, mobile phase is methanol-water (75:25), and detection wavelength is 270 nm. Ischemia-reperfusion injury model is replicated, and the size of myocar...
متن کاملMetabolism of tanshinone IIA, cryptotanshinone and tanshinone I from Radix Salvia miltiorrhiza in zebrafish.
The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds, and their metabolites mediated by zebrafish were characterized using a high-performance liquid chromatography ...
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During the last decade, a more detailed knowledge of molecular mechanisms involved in osteoclastogenesis has driven research efforts in the development and screening of compound libraries of several small molecules that specifically inhibit the pathway involved in the commitment of the osteoclast precursor cells. Natural compounds that suppress osteoclast differentiation may have therapeutic va...
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Tanshinone IIA is one of the active principles in danshen (Salvia miltiorrhiza Bge) widely used in treatment of cardiovascular disorders. We investigated the effect of danshen or tanshinone IIA on blood pressure and its possible mechanisms. An i.p. injection of danshen at 10 mg kg(-1) significantly lowered systolic blood pressure (SBP) of spontaneously hypertensive rats (SHRs) but failed to mod...
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A natural male sterile mutant of Salvia miltiorrhiza (Labiatae, Sh-B) was found during field survey in 2002. Our objective was to analyze its genetic mechanism for producing F1 hybrid seeds and to develop a molecular marker linked to male sterile gene for selection of a hybrid parent line. The segregation ratios of male sterile plants to fertile plants in the progenies of both testcross and bac...
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ژورنال
عنوان ژورنال: Dermatologica Sinica
سال: 2021
ISSN: 1027-8117
DOI: 10.4103/ds.ds_1_21